About Me
Research Interest
I currently focusing on several topics like Computational drug design and bioinformatics on Covid 19; follow up studis in different epidemiological disorder, medicinal plants and secondary metabolites, precision medicine especially emphasized on DNA aptamer based drug discovery for cancer treatment; anticancer effects of arsenic trioxide and its metabolites on PML-RARA fusion protein degradation in acute promyelocytic leukemia (APL), additionally the epidemiological study on arsenic toxicity in human etc.
Professional & Other Experiences
1. March 15, 2014-till to-date
Assistant Professor, Department of Biochemistry and Molecular Biology, Mawlana Bhashani Science and Technology University
2. July15, 2013- March 15, 2014
Lecturer, Department of Biochemistry and Biotechnology, Khwaja Yunus Ali University
3. Feb. 2, 2011- July 14, 2013
Biochemist, Popular Diagnostic Center (Bangladesh) Limited
4. Feb. 1, 2008- March 15, 2009
Quality Control Officer, Renata Pharmaceuticals (Bangladesh) Limited
Education
1. 2015-2017
Postdoctoral Fellow, Zhejiang University, China
2. 2013
PhD, Institute of Biological Sciences University of Rajshahi
3. 2005 (Held in 2007)
M. Sc, University of Rajshahi
4. 2004 (Held in 2005)
B.Sc (Hon’s), University of Rajshahi
5. 2000
H.S.C, Rajshahi New Govt. Degree College
6. 1998
S.S.C, Nawabgonj Horimohan Govt. High School.
Publications
2. Mohammod Johirul Islam1, Titash Chandra Sarker, Ruksana Akter Jebin, Farjana Yasmin, Mousumi Khatun1, Md. Ashraful Islam, Sadia Binte Ramzan, Fahim Alam Nobel, Sharmin Akter, Monira Islam, Mohammad Mehedi Hasan, Mst. Mahmuda Khatun, Shahnaz Yesmin, Saima Sabrina, Marina Khatun, Abdullah Al Mamun, Md. Khairul Islam, Mohammad Asaduzzaman, Keshob Chandra Das, Mohammed Badrul Amin, and Mohammad Khaja Mafij Uddin. Determination of Optimum Survivability Factors of Highly Pathogenic Vibrio cholerae 01 Serogroup-Specific Bacteriophage JSF4ϕ. American Journal of Pure and Applied Biosciences. 2020, 2(2), 8-14.
3. Abdullah Al Mamun, Md. Sohel, Majharul Islam, Mst. Mahmuda Khatun, Suraiya Aktar, Ashekul Islam, Khairul Islam & Md Masuder Rahman. Epidemiological Information about COVID-19 Outbreak in Bangladesh: A Descriptive Study. EAS Journal of Parasitology and Infectious Diseases. 2020 July-Aug, 2(4).|
4. Mondal V, H Zubaer, Hossen F, Siddique A E, Tonya S R, Islam Z, Islam M S, Hossain S, Islam K, Sarker M K, Hasibuzzaman M M, Liu L, Jiang B H, Hoque M M, Saud Z A, Xin L, Himeno S, Hossain K. Arsenic exposure-related hyperglycemia is linked to insulin resistance with concomitant reduction of skeletal muscle mass. Environ Int. 2020 October, 143, 105890.
5. Yang C, Wang Y, Ge MH, Fu YJ, Hao R, Islam K, Huang P, Chen F, Sun J, Hong F, Naranmandura H. Rapid identification of specific DNA aptamers precisely targeting CD33 positive leukemia cells through a paired cell-based approach. Biomater Sci. 2019 Feb 26;7(3):938-950. doi: 10.1039/c8bm01393d.
6. Maimaitiyiming Y, Wang C, Xu S , Islam K , Chen YJ , Yang C , Wang QQ , Naranmandura H, Role of arsenic (+3 oxidation state) methyltransferase in arsenic mediated APL treatment: an in vitro investigation. Metallomics. 2018 Jun 20;10(6):828-837. doi: 10.1039/c8mt00057c.
7. Islam K, Islam MN, Uddin MM and Mamun AA. Antibacterial, Cytotoxic and Analgesic Activities of the Ethanol Extract of Feronia Limonia Linn Fruit Pulp, IOSR Journal of Pharmacy and Biological Sciences (IOSR-JPBS) 2018 Apr 13(2) PP 31-37.
8. Islam K, Wang QQ, Jiang YH, Wang C, Naranmandura H, Metabolism, toxicity and anticancer activities of arsenic compounds. Oncotarget, 2017 Apr 4;8(14):23905-23926. doi: 9.18632/oncotarget.14733.
9. Huang P, Zhang YH, Zheng XW, Liu YJ, Zhang H, Fang L, Zhang YW, Yang C, Islam K, Wang C, Naranmandura H. Phenylarsine oxide (PAO) induces apoptosis in HepG2 cells via ROS-mediated mitochondria and ER-stress dependent signaling pathways. Metallomics. 2017 Dec 1;9(12):1756-1764. doi: 10.1039/c7mt00179g. Epub 2017 Aug 23.
10. Jiang YH, Chen YJ, Wang C, Lan YF, Yang C, Wang QQ, Hussain L, Maimaitiying Y, Islam K, Naranmandura H. Phenylarsine Oxide Can Induce the Arsenite-Resistance Mutant PML Protein Solubility Changes. Int J Mol Sci. 25;18(2). pii: E247, Jan 2017.
11. K Islam, QQ Wang, H Naranmandura. Molecular Mechanisms of Arsenic Toxicity. Advances in Molecular Toxicology 9, 77-107.
12. Sultana C, Azad A.K., Kundo NK, Siddik AB, Islam K and Wahed MII, Antioxidant, analgesic and in-vitro thrombolytic activities of ethanolic extract of peperomiaPellucida (l.). Inter. J. of Phytotherapy / Vol 5 / Issue 4 / 2015 / 143-147
13. Rahman M, Mamun AA, Karim MR, Islam K, Amin HA, Hossain S, Hossain MI, Saud ZA, Noman AS, Miyataka H, Himeno S, Hossain K, Associations of total arsenic in drinking water, hair and nails with serum vascular endothelial growth factor in arsenic-endemic individuals in Bangladesh, Chemosphere, 120, 336-342, August, 2014
14. Huda N, Hossain S, Rahman M, Karim MR, Islam K, Mamun AA, Hossain MI, Mohanto NC, Alam S, Aktar S, Arefin A, Ali N, Salam KA, Aziz A,Saud ZA, Miyataka H, Himeno S, Hossain K, Elevated levels of plasma uric acid and its relation to hypertension in arsenic-endemic human individuals in Bangladesh, ToxicolApplPharmacol, 2;281(1):11-18. October, 2014
15. Sheikh A, Yeasmin F, Agarwal S, Rahman M, Islam K, Hossain E, Hossain S, Karim MR, Nikkon F, Saud ZA, Hossain K, Protective effects of Moringaoleifera Lam. leaves against arsenic-induced toxicity in mice. Asian Pac J Trop Biomed, 4, 353-358. April, 2014
16. Karim MR, Rahman M, Islam K, Mamun AA, Hossain S, Hossain E, Aziz A, Yeasmin F, Agarwal S, Hossain MI, Saud ZA, Nikkon F, Hossain M, Mandal A, Jenkins RO, Haris PI, Miyataka H, Himeno S, Hossain K, Increases in Oxidized Low-Density Lipoprotein and Other Inflammatory and Adhesion Molecules With a Concomitant Decrease in High-Density Lipoprotein in the Individuals Exposed to Arsenic in Bangladesh, Toxicol Sci,135, 17-25, June, 2013
17. Rahman M, Saud ZA, Hossain E, Islam K, Karim MR, Yeasmin T, Nikkon F, Mandal A, Hossain K, Ameliorating Effects OfZinziber Zerumbet Linn. On Sodium Arsenite Induced Changes Of Blood Indices In Experimental Mice, Life Sciences and Medicine Research, 41, 1-11, February, 2012
18. Islam K*, Hossain E*, Yeasmin F, Karim MR, Rahman M, Agarwal S, Hossain S, Aziz A, Mamun AA, Sheikh A, Haque A, Hossain MT, Hossain M, Haris PI, Ikemura N, Inoue K, Miyataka H, Himeno S and Hossain K, Elevated levels of plasma Big endothelin-1 and its relation to hypertension and skin lesions in individuals exposed to arsenic, ToxicolApplPharmacol, 259, 187-194, January, 2012*equally contributed.
19. Islam K, Haque A, Karim MR, Fajol A, Hossain E, Salam KA, Ali N, Saud ZA, Rahman M, Rahman M, Karim R, Sultana P, Hossain M, Akhand AA, Mandal A, Miyataka H, Himeno S, Hossain K, Dose-response relationship between arsenic exposure and the serum enzymes for liver function tests in the individuals exposed to arsenic: a cross sectional study in Bangladesh, Environ Health, 10, 64, July, 2011
20. Karim MR, Salam KA, Hossain E, Islam K, Ali N, Haque A, Saud ZA, Yeasmin T, Hossain M, Miyataka H, Himeno S, Hossain K, Interaction between arsenic exposure via drinking water and plasma lactate dehydrogenase activity, Sci Total Environ, 409, 278-283, October, 2010
21. Ali N, Md. Hoque A, Haque A, Salam KA, Karim MR, Rahman A, Islam K, Saud ZA, Khalek MA, Akhand AA, Hossain M, Mandal A, Karim MR, Miyataka H, Himeno S and Hossain K, Association between arsenic exposure and plasma cholinesterase activity: a population based study in Bangladesh, Environ Health, 9, 36, July, 2010
22. Karim MR, Haque A, Islam K, Ali N, Salam KA, Saud ZA, Hossain E, Fajol A, Akhand AA, Himeno S, Hossain K, Protective effects of the dietary supplementation of turmeric (Curcuma longa L.) on sodium arsenite-induced biochemical perturbation in mice, Bangladesh Med Res Counc Bull, 36, 82-88, 2010.
2.Best poster presentation award in Bangladesh Society for Biochemistry and Molecular Biology 2012.
3.Best poster presentation award in Zoha Memorial symposium 2011, Organized by Dept. of Chemistry, Rajshahi, Bangladesh. National Science Information and Communication Technology fellowship 2011and 2012.

