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Publications

Abstract

Background

Endoscopy has long been widely used to screen for esophageal varices (EV) in cirrhotic patients. Recurrent endoscopy is a significant burden for the healthcare system of the endoscopic unit as well as uncomfortable and high costs for patients. This study intended to prognosticate Right Liver Lobe Diameter/Serum Albumin Ratio (RLLD/Alb) as a non-invasive approach in the early diagnosis of EV among chronic liver disease (CLD) Bangladeshi patients enrolled in a specific hospital.

Participants and Methods

A total of 150 admitted patients with CLD were included in the study. Patients were subjected through a comprehensive biochemical checkup and upper digestive endoscopic or ultrasonographic inspection. The correlation was evaluated between the RLLD/Alb ratio and esophageal varices grades.

Results

The upper digestive endoscopy demonstration among 150 patients resulted in no EV in 18%, while 24% of patients was identified as EV grade I, 20% as grade II, 20% as grade III, and 18% patients as grade IV. The mean value of the RLLD/Alb ratio was 4.89 ± 1.49 (range from 2.30 to 8.45). The RLLD/Alb ratio diagnosed the EV employing the cut-off value of 4.01 with 85.3% sensitivity and 68.8% specificity. Furthermore, it was positively correlated with the grading of EV, when this ratio increased the grading of EV increases and vice versa (r = 0.630, p < 0.001).

Conclusion

The RLLD/Alb ratio is a non-invasive parameter giving exact guidance relevant to the ascertainment of the existence of EV and their grading in chronic liver disease patients.

Pulak Kanti Palit, Ashekul Islam , Md Syeed Al Habib , Abu Syed Mohammed Mujib, Joyonti Datta, Bahni Chakraborty , Suman Dhar , Dhiman Chowdhury, Md Faisal Fahad Chowdhury , Mohammad Shawkat Ali , Arfana Yesmin , Mohammod Johirul Islam , Nishat Akther , Abdullah Al Mamun , Khairul Islam and Pradip Kumar Nath

"“Poor glycemic control enhances the disease activity in the RA patients with undiagnosed diabetes—a cross-sectional clinical study”" Egyptian Rheumatology and Rehabilitation , Others

Rahaman, M. A.; Mousavi, B.; Shahadat, H. M.; Akther, N.; Luo, Z.; Zuiykov, S.; Verpoort, F.,

"Ring-opening copolymerization of ε-caprolactone and δ-valerolactone by Titanium-based metal-organic framework" New Journal of Chemistry , Others , 2021

Fahim Alam Nobel, Sharmin Akter1, Ruksana Akter Jebin, Titash Chandra Sarker, Md. Mizanur Rahman, Saad Al Zamane, Khairul Islam, Saima Sabrina, Nishat Akther, Ashekul Islam, Md. Rakibul Hasan, Mohammod Johirul Islam.,

"Prevalence of multidrug resistance patterns of Escherichia coli from suspected urinary tract infection in Mymensingh city, Bangladesh." Journal of Advance Biotechnology and Experimental Therapeutics. , Others , 2021

Akther, N.; Abdur, R. M.; Amjad, H. M.; Foysol, R. M.; Afroze, S.; Akter, F.; Johirul, I. M.; Hossain, M. N

"In vitro assessment of quantitative analysis of phytochemicals, iron (II) chelating activity and antimicrobial efficacy of methanolic solvent extract of citrus maxima leaf." Journal of Pharmacognosy and Phytochemistry , Others , 2021

Abdur, R. M.; Mousavi, B.; Shahadat, H. M.; Akther, N.; Chaemchuen, S.; Verpoort, F.,

"High Molecular Weight Poly (methyl methacrylate) Synthesis Using Recyclable and Reusable Zeolitic Imidazole Framework‐8 Catalyst." Macromolecular Chemistry and Physics , Others , 2020

Matin, M.; Bhuiyan, M.; Azad, A.; Akther, N

"Design and synthesis of benzyl 4-O-lauroyl-α-L-rhamnopyranoside derivatives as antimicrobial agents." Current Chemistry Letters , Others , 2017

Hossain, M. N.; Akther, N.; Alauddin, M.; Bhuiyan, R. H.; Hossain, M. M.; Rahaman, M. A.,

"In Vitro Interaction Between Oral Hypoglycemic Drug And Herbal Sex Stimulants: Drug Interactions." European Scientific Journal , Others , 2016

Bhowmick, A. C.; Rahaman, M. A.; Islam, M.; Akther, N.; Hossain, M. S.; Patwary, M. M.,

"Comparative adsorption study on rice husk and rice husk ash by using amaranthus gangeticus pigments as dye." European Scientific Journal , Others , 2015

Rahaman, M. A.; Hossain, M. S.; Hossain, M. K.; Akhtar, S.; Akther, N

"Densities, Refractive Indices And Derived Properties Of N-Heptane With Some Aromatic Hydrocarbons At 298.15 K." Journal of Science and Technology , Others , 2015