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Protein Interactome Offers Key Resource for Drug Discovery and Repurposing

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Protein Interactome Offers Key Resource for Drug Discovery and Repurposing

Interaction networks can be used to expand the list of candidate genes associated with traits and diseases identified through genome-wide association studies. A new study has uncovered genes linked to over 1000 human traits from 21 therapeutic areas. Using inflammatory bowel disease (IBD) as an example, the researchers showed that the interactome could be used to find proteins most likely to be involved in causing disease.