Md Sohel, Moushumi Akter, Md. Fahmid Hasan, Shahin Mahmud , Mohammod Johirul Islam, Ashekul Islam, Khairul Islam, and Abdullah Al Mamun*. “Antibiotics Resistance Pattern of Food-Borne Bacteria Isolated from Ice Cream in Bangladesh: A Multidisciplinary Study”. Journal of Food Quality, 2022: 5016795. DOI: https://doi.org/10.1155/2022/5016795

Abstract

Background

Endoscopy has long been widely used to screen for esophageal varices (EV) in cirrhotic patients. Recurrent endoscopy is a significant burden for the healthcare system of the endoscopic unit as well as uncomfortable and high costs for patients. This study intended to prognosticate Right Liver Lobe Diameter/Serum Albumin Ratio (RLLD/Alb) as a non-invasive approach in the early diagnosis of EV among chronic liver disease (CLD) Bangladeshi patients enrolled in a specific hospital.

Participants and Methods

A total of 150 admitted patients with CLD were included in the study. Patients were subjected through a comprehensive biochemical checkup and upper digestive endoscopic or ultrasonographic inspection. The correlation was evaluated between the RLLD/Alb ratio and esophageal varices grades.

Results

The upper digestive endoscopy demonstration among 150 patients resulted in no EV in 18%, while 24% of patients was identified as EV grade I, 20% as grade II, 20% as grade III, and 18% patients as grade IV. The mean value of the RLLD/Alb ratio was 4.89 ± 1.49 (range from 2.30 to 8.45). The RLLD/Alb ratio diagnosed the EV employing the cut-off value of 4.01 with 85.3% sensitivity and 68.8% specificity. Furthermore, it was positively correlated with the grading of EV, when this ratio increased the grading of EV increases and vice versa (r = 0.630, p < 0.001).

Conclusion

The RLLD/Alb ratio is a non-invasive parameter giving exact guidance relevant to the ascertainment of the existence of EV and their grading in chronic liver disease patients.

Md Sohel, Habiba Sultana, Tayeba Sultana, Abdullah Al Mamun, Mohammad Nurul Amin,  Md. Arju Hossain, Md. Chayan Ali, Suraiya Aktar, Armin Sultana, Zahed Bin Rahim, Sarmistha Mitra, Raju dash*. “Chemotherapeutics activities of dietary phytoestrogens against prostate cancer: From observational to clinical studies”. Current Pharmaceutical Design, 2022, 28(19):1561-1580. DOI: 10.2174/1381612828666220601153426.